3-(4-methylpiperazin-1-yl)phenylboronic acid

3-(4-methylpiperazin-1-yl)phenylboronic acid - Names and Identifiers

Name	3-(4-methylpiperazin-1-yl)phenylboronic acid
Synonyms	3-(4-methylpiperazinyl)phenyl boronic acid 3-(4-Methyl-1-piperazinyl)phenylboronic Acid 3-(4-methylpiperazin-1-yl)phenylboronic acid B-[3-(4-methyl-1-piperazinyl)phenyl]Boronic acid Boronic acid, B-[3-(4-methyl-1-piperazinyl)phenyl]-
CAS	1139717-76-2

3-(4-methylpiperazin-1-yl)phenylboronic acid - Physico-chemical Properties

Molecular Formula	C11H17BN2O2
Molar Mass	220.07588
Density	1.20
Boling Point	417.7±55.0 °C(Predicted)
pKa	8.79±0.10(Predicted)
Storage Condition	2-8℃

3-(4-methylpiperazin-1-yl)phenylboronic acid - Introduction

3-(4-methylpiperazin-1-yl)phenylboronic acid is an organic compound with the chemical formula C12H16BNO2. It has the form of a white crystal or powder.

3-(4-methylpiperazin-1-yl)phenylboronic acid is commonly used as an intermediate in organic synthesis, especially in Suzuki coupling reactions catalyzed by phenylboronic acid compounds. It can be reacted with aromatic halides or coupling reagents to prepare organic compounds with more complex structures. In addition, it can also be used in the study of compound synthesis in the pharmaceutical field.

The method for preparing 3-(4-methylpiperazin-1-yl)phenylboronic acid is usually obtained from the reaction of 3-bromophenylboronic acid and 4-methyl piperazine. First, 3-bromophenylboronic acid is treated with a base to form its corresponding boronic acid. Then, 4-methylpiperazine is reacted with the generated boric acid, and the target product can be obtained under appropriate conditions.

Regarding safety information, 3-(4-methylpiperazin-1-yl)phenylboronic acid currently has no clear hazardous material identification and Hazard description. However, as a chemical, it still needs to be handled properly, avoiding contact with the skin, eyes and respiratory tract. Wear appropriate personal protective equipment such as lab gloves and goggles during use. In case of discomfort or contact accident, seek medical help immediately. In addition, it should be stored in a dry, cool, well-ventilated place, away from fire sources and flammable materials.

Last Update：2024-04-09 21:01:54